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Fig. 2.

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Fig. 2. Fundus photographs and optical coherence tomography (OCT) images of a case of age-related macular degeneration treated with intravitreal aflibercept treat-and-extend regimen. (A, B) At diagnosis, best-corrected visual acuity (BCVA) was 0.15. (C) Subretinal fluid (SRF) was decreased after three monthly aflibercept injections. BCVA was 0.2. (D) Eight weeks after the fourth intravitreal aflibercept injection, OCT showed persistent SRF with unchanged fluid. BCVA was 0.2. There was no visual loss. So, the patient was treated with a fifth intravitreal aflibercept injection at an interval of 8 weeks to maintain the injection interval. (E) Eight weeks after the fifth intravitreal aflibercept injection, OCT showed complete absorption of SRF. BCVA was 0.3. The patient was treated with a sixth intravitreal aflibercept injection at an interval of 10 weeks to extend the injection interval. (F) Ten weeks after the sixth intravitreal aflibercept injection, there was no fluid on OCT. BCVA was 0.3. The patient was treated with a seventh intravitreal aflibercept injection at an interval of 12 weeks to further extend the injection interval.
J Retin 2021;6:99-109 https://doi.org/10.21561/jor.2021.6.2.99
© 2021 J Retin