pISSN 2508-1926

Categorical change in UACR both before and after IVB (by regression to the mean)

Categorical change of UACR | DME (n = 30) | No DME (n = 23) | |
---|---|---|---|

A1 Residual decrease | 6 (20) | 7 (30) | 0.576 |

A1 Regression to the mean | 3 (10) | 1 (4) | |

A2 Residual decrease | 4 (13) | 3 (13) | 0.930 |

A2 Regression to the mean | 4 (13) | 4 (17) | |

A2 Residual increase | 3 (10) | 2 (9) | |

A3 Regression to the mean | 3 (10) | 0 | 0.250 |

A3 Residual increase | 7 (23) | 6 (26) | |

0.009 | <0.001 |

Values are presented as number (%). Categorical change of UACR by baseline category is as follows: 1) for A1, residual decrease implied minor change or decrease of UACR ≥ 30%, and regression to the mean implies increase of UACR ≥ 30%; 2) for A2, residual decrease indicated decrease of UACR ≥ 30%, regression to the mean implied a minor change, and residual increase implied increase of UACR ≥ 30%; and 3) for A3, regression to the mean suggested decrease of UACR ≥ 30%, and residual increase implied increase of UACR ≥ 30% or minor change.

UACR = urinary albumin-to-creatinine ratio; IVB = intravitreal bevacizumab injection; DME = diabetic macular edema.

Fisher’s exact test;

chi-square test.

J Retin 2019;4:69-76 https://doi.org/10.21561/jor.2019.4.2.69

© 2019 J Retin