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Table. 5.

Table. 5.

Categorical change in UACR both before and after IVB (by regression to the mean)

Categorical change of UACR DME (n = 30) No DME (n = 23) p-value
A1 Residual decrease 6 (20) 7 (30) 0.576*
A1 Regression to the mean 3 (10) 1 (4)
A2 Residual decrease 4 (13) 3 (13) 0.930
A2 Regression to the mean 4 (13) 4 (17)
A2 Residual increase 3 (10) 2 (9)
A3 Regression to the mean 3 (10) 0 0.250*
A3 Residual increase 7 (23) 6 (26)
p-value 0.009 <0.001

Values are presented as number (%). Categorical change of UACR by baseline category is as follows: 1) for A1, residual decrease implied minor change or decrease of UACR ≥ 30%, and regression to the mean implies increase of UACR ≥ 30%; 2) for A2, residual decrease indicated decrease of UACR ≥ 30%, regression to the mean implied a minor change, and residual increase implied increase of UACR ≥ 30%; and 3) for A3, regression to the mean suggested decrease of UACR ≥ 30%, and residual increase implied increase of UACR ≥ 30% or minor change.

UACR = urinary albumin-to-creatinine ratio; IVB = intravitreal bevacizumab injection; DME = diabetic macular edema.

Fisher’s exact test;

chi-square test.

J Retin 2019;4:69-76 https://doi.org/10.21561/jor.2019.4.2.69
© 2019 J Retin