eISSN 2508-3589
pISSN 2508-1926
pISSN 2508-1926
Overview of types of uveal melanoma according to The Cancer Genome Atlas (TCGA) classification
| A | B | C | D | |
|---|---|---|---|---|
| Gene expression profile | Class 1 | Class 1 | Class 2 | Class 2 |
| Chromosome aberration | Infrequent | Infrequent | Frequent | Frequent |
| Chromosome 3 | Disomy 3 | Disomy 3 | Monosomy 3 | Monosomy 3 |
| Chromosome 8 | Normal 8q | Partial extra 8q | Extra 8q | Extra 8q |
| Gene alteration | EIF1AX | SF3B1 | BAP1-aberrant | BAP1-aberrant |
| Inflammation | None | None | Some | Much |
| Prognosis | Favorable | Late metastases | Unfavorable | Unfavorable |