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Fig. 2.

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Fig. 2. (A) Optical coherence tomography angiography (OCTA) (Cirrus HD-OCT 5000; Carl Zeiss Meditech, Berlin, Germany) of the superficial retinal layers before switching to brolucizumab. The vessel density (VD) of the entire 6 × 6 mm image was 7.67 mm/mm2 (yellow box). (B) Four weeks after the first brolucizumab injection, the VD slightly increased to 8.35 mm/mm2 (yellow box). (C) Eight weeks after the first brolucizumab injection, the patient experienced intraocular inflammation (IOI) and retinal occlusive vasculitis (ROV). The VD dramatically decreased to 6.76 mm/ mm2 (yellow box). (D) After 1 week of topical corticosteroid and oral prednisolone treatment, the VD had recovered to 7.56 mm/mm2 (yellow box). (E) The superficial retinal layer VD before and after brolucizumab injection shows that the VD decreased dramatically at the onset of IOI and had recovered after 1 week of topical corticosteroid and oral prednisolone. wk = weeks.
J Retin 2022;7:59-64 https://doi.org/10.21561/jor.2022.7.1.59
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