eISSN 2508-3589
pISSN 2508-1926
pISSN 2508-1926
Demographic characteristics and clinical features of subjects
| Characteristic | Hyperhomocysteinemia | Normal | p-value |
|---|---|---|---|
| Patients (eyes) | 34 | 86 | |
| Sex, male:female | 18:16 | 33:53 | 0.146 |
| Age (years) | 59.34 ± 16.23 | 65.65 ± 2.12 | 0.005 |
| Diagnosis, BRVO/CRVO | 12 (35.29)/22 (64.70) | 50 (58.14)/36 (41.86) | 0.024 |
| Diabetes | 14 (41.18) | 11 (12.79) | < 0.001 |
| Hypertension | 22 (64.71) | 25 (25.07) | < 0.001 |
| CVA history | 3 | 1 | 0.122 |
| BCVA (logMAR) | 0.16 ± 0.20 | 0.09 ± 0.33 | 0.286 |
| Spherical equivalent (diopters) | -0.36 ± 1.69 | -0.71 ± 1.52 | 0.287 |
| IOP (mmHg) | 12.47 ± 2.98 | 13.63 ± 0.71 | 0.070 |
| Serum homocysteine (nmol/mL) | 20.16 ± 6.33 | 9.31 ± 2.25 | < 0.001 |
| Vitamin B12 (pg/mL) | 546.78 ± 236.00 | 509.81 ± 265.91 | 0.427 |
| Vitamin B6 (nmol/mL) | 26.21 ± 11.41 | 24.33 ± 12.32 | 0.245 |
| Folate (ng/mL) | 12.94 ± 6.65 | 14.98 ± 5.90 | 0.201 |
Values are present as mean ± standard deviation or number (%) unless otherwise indicated.
BRVO = branch retinal vein occlusion; CRVO = central retinal vein occlusion; CVA = cerebrovascular attack; BCVA = best corrected visual acuity; logMAR = logarithm of the minimum angle of resolution; IOP = intraocular pressure.
*By chi-square test; †by independent t-test.